What is Phosphatidylserine?

Phosphatidylserine (PS) is a phospholipid, a type of fat molecule, that is a vital component of cell membranes in the human body. It is primarily found in the brain, where it plays an important role in maintaining cell structure and function.

Where does Phosphatidylserine come from?

Phosphatidylserine can be found in small amounts in some foods, such as soybeans and beef, but it is typically extracted from animal sources, such as bovine or porcine brain tissue, for use in supplements.

What are the effects of Phosphatidylserine?


Phosphatidylserine is primarily known for its ability to improve memory and attention in aging adults. Research suggests that taking phosphatidylserine supplements may help to slow down cognitive decline and improve cognitive function in individuals with mild cognitive impairment.


Phosphatidylserine has also been studied for its potential effects on physical performance. Some research suggests that it may help to reduce exercise-induced stress and improve exercise capacity in athletes.

How to use Phosphatidylserine?

Phosphatidylserine is available in supplement form and is typically taken orally. It is often included in "brain health" or "memory" supplements, and may also be marketed as a standalone supplement.

How much Phosphatidylserine to use?

The recommended dosage of phosphatidylserine varies depending on the individual and the reason for use. Generally, a dosage of 100-300 mg per day is recommended for cognitive support, while a dosage of up to 600 mg per day may be used for physical performance enhancement.

When trying out new supplements it is wise to start with a lower dose and–depending on the experienced effects–increase or decrease the dosage accordingly

It is important to consult with a healthcare professional before starting to use any new supplement, including phosphatidylserine.

What are the side effects of Phosphatidylserine?

Phosphatidylserine is generally considered safe for most people when taken at recommended dosages. However, some people may experience mild side effects such as stomach upset, headache, or insomnia.

Interactions of Phosphatidylserine

Phosphatidylserine may interact with certain medications, including blood-thinning medications, and should not be used by individuals who are taking these medications without consulting with a healthcare professional.

Overall, phosphatidylserine is a promising supplement for improving cognitive function and potentially enhancing physical performance, but as with any supplement, it is important to use it responsibly and under the guidance of a healthcare professional.

Other namesPS, PtdSer, Phospholipid