Uridine Monophosphate

What is Uridine Monophosphate?

Uridine Monophosphate (UMP) is a naturally occurring nucleotide that serves as a building block for RNA molecules. It plays an essential role in various biological processes, including the regulation of gene expression, maintenance of cellular membranes, and synthesis of the neurotransmitter acetylcholine. Recent research has indicated that UMP supplementation may offer cognitive-enhancing effects and improve overall brain health.

Where does Uridine Monophosphate come from?

Uridine Monophosphate is found in various food sources, such as tomatoes, broccoli, beer, and offal (organ meats). It is also produced in the human body through the breakdown of RNA. In addition, UMP is available as a dietary supplement in the form of capsules, powders, and sublingual tablets.

What are the effects of Uridine Monophosphate?


  • Improved memory formation and recall
  • Enhanced focus and attention
  • Increased synaptic plasticity
  • Potential neuroprotective effects


  • Supports cellular membrane integrity
  • Promotes overall brain health
  • May aid in the synthesis of phosphatidylcholine, an essential component of cell membranes

How to use Uridine Monophosphate?

Uridine Monophosphate can be consumed as a dietary supplement in capsule, powder, or sublingual tablet form. It is generally advised to start with a low dosage and gradually increase as needed. UMP can be taken with or without food and is often stacked with other nootropics to enhance cognitive benefits.

How much Uridine Monophosphate to use?

When trying out new supplements it is wise to start with a lower dose and–depending on the experienced effects–increase or decrease the dosage accordingly

The recommended starting dose of UMP is 50 mg daily, with some individuals opting for higher dosages of up to 500 mg per day. It is important to consult a healthcare professional before starting any supplementation regimen and to closely monitor for potential side effects.

What are the side effects of Uridine Monophosphate?

UMP is generally well-tolerated with few reported side effects. However, some individuals may experience gastrointestinal distress, headache, or fatigue. In rare cases, allergic reactions may occur. If you experience any adverse effects, discontinue use and consult a healthcare professional.

Interactions of Uridine Monophosphate

Most nootropics are relatively safe to use on their own. Combining them with other substances may cause them to suddenly become dangerous or life-threatening.

Although Uridine Monophosphate is considered safe, it may interact with certain medications or have contraindications for individuals with specific medical conditions. Consult a healthcare professional before starting any supplementation regimen, especially if you are taking prescription medications or have a pre-existing medical condition.

NameUridine Monophosphate
Other namesUMP, 5'-uridylic acid
EffectsMemory, Focus